Indoxyl sulfate upregulates renal expression of icam-1 via production of ros and activation of nf-κb and p53 in proximal tubular cells

• Κύριοι συγγραφείς: Hidehisa Shimizu (Συγγραφέας), Toshimitsu Niwa (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: The Korean Society of Nephrology, 2012-06-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Intercellular adhesion molecule 1 (ICAM-1) plays an important role in adhesion of monocytes/macrophages to injured tubulointerstitial tissue. The present study examined whether indoxyl sulfate, a uremic toxin, regulates renal expression of ICAM-1. The effect of indoxyl sulfate on expression of ICAM-...