Fasting hyperglycemia in the Goto-Kakizaki rat is dependent on corticosterone: a confounding variable in rodent models of type 2 diabetes
SUMMARY The Goto-Kakizaki (GK) rat is an inbred model of type 2 diabetes (T2D); GK rats are lean but have hyperglycemia and increased gluconeogenesis. However, fasting hyperglycemia in other commonly used rodent models of T2D is associated with increased corticosterone, and thus the underlying mecha...
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Main Authors: | Sara A. Beddow (Author), Varman T. Samuel (Author) |
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Format: | Book |
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The Company of Biologists,
2012-09-01T00:00:00Z.
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