Lycorine Induces Mitochondria-Dependent Apoptosis in Hepatoblastoma HepG2 Cells Through ROCK1 Activation

• Main Authors: Wu-yi Liu (Author), Qin Tang (Author), Qian Zhang (Author), Chang-peng Hu (Author), Jing-bin Huang (Author), Fang-fang Sheng (Author), Ya-li Liu (Author), Min Zhou (Author), Wen-jing Lai (Author), Guo-bing Li (Author), Rong Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lycorine, a naturally occurring compound extracted from the Amaryllidaceae plant family, has been reported to exhibit antitumor activity in various cancer cell types. In the present study, we investigated the molecular mechanisms underlying lycorine-induced apoptosis in hepatoblastoma HepG2 cells. W...