Anti-tumor effect of antibody-drug conjugate targeting cell adhesion molecule 1 on GIST cells representing small intestinal GIST

• Main Authors: Makoto Yoshida (Author), Jiayin Yuan (Author), Takako Kihara (Author), Neinei Kimura (Author), Takashi Yamasaki (Author), Mizuka Ohkouchi (Author), Yuka Hashikura (Author), Koji Isozaki (Author), Man Hagiyama (Author), Akihiko Ito (Author), Seiichi Hirota (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the alimentary tract. The prognosis depends on the primary site, and small intestinal GISTs have a worse prognosis than gastric GISTs. Molecularly targeted drugs to inhibit tyrosine kinase activity of KIT were used for unr...