Polysaccharide dextran-based conjugate for selective co-delivery of two synergistic drugs docetaxel and docosahexaenoic acid to tumor cells

• Main Authors: Peng Dong (Author), Hongshuai Lv (Author), Weiping Jia (Author), Jiaojiao Liu (Author), Si Wang (Author), Xiaohai Li (Author), Jinghua Hu (Author), Ling Zhao (Author), Yikang Shi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractMost chemotherapeutic agents are nonspecific distribution and cause systemic toxicities. Polysaccharide-based conjugates are promising strategies to overcome these drawbacks. To this end, two synergistic drugs docetaxel (DTX) and docosahexaenoic acid (DHA) were independently covalently bonde...