A change in circulating chikungunya virus variant impacts Aedes aegypti vector competence and spatiotemporal distribution of disease in Malaysia.

• Main Authors: Izzati Kausar Azman (Author), Yoke Fun Chan (Author), Chong Long Chua (Author), Zainal Abidin Abd Mutalib (Author), Sarat Chandra Dass (Author), Balvinder Singh Gill (Author), Nor Hayati Ismail (Author), Jenarun Jelip (Author), Ming Keong Wan (Author), Wenn-Chyau Lee (Author), Indra Vythilingam (Author), Luke Alphey (Author), I-Ching Sam (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>In 2008-2010, Malaysia experienced a nationwide chikungunya virus (CHIKV) outbreak caused by the Indian Ocean lineage E1-226V (valine) variant, adapted to Aedes albopictus. In 2017-2022, transition to an E1-226A (alanine) variant occurred. Ae. albopictus prevails in ru...