Crimean-Congo hemorrhagic fever virus strains Hoti and Afghanistan cause viremia and mild clinical disease in cynomolgus monkeys.

• Hlavní autoři: Robert W Cross (Autor), Abhishek N Prasad (Autor), Viktoriya Borisevich (Autor), Joan B Geisbert (Autor), Krystle N Agans (Autor), Daniel J Deer (Autor), Karla A Fenton (Autor), Thomas W Geisbert (Autor)
• Médium: Kniha
• Vydáno: Public Library of Science (PLoS), 2020-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

<h4>Background</h4>Development of vaccines and therapies against Crimean-Congo hemorrhagic fever virus (CCHFV) have been hindered by the lack of immunocompetent animal models. Recently, a lethal nonhuman primate model based on the CCHFV Hoti strain was reported. CCHFV Hoti caused severe...