Selectivity of Ca2+ channel blockers for dilator actions on the isolated lower esophageal sphincter and aorta from rats

Selectivity of Ca2+ channel blockers for dilator actions on the isolated lower esophageal sphincter and aorta from rats

We compared dilator actions of representative four Ca2+ channel blockers on the isolated lower esophagus sphincter (LES) and thoracic aorta from rats. Verapamil, diltiazem, nifedipine and cilnidipine suppressed KCl-induced contractions of LES and thoracic aorta in a concentration-dependent manner. T...

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Main Authors: Akira Takahara (Author), Shuhei Nozaki (Author), Akane Ishiguro (Author), Kaori Okamura (Author), Xin Cao (Author), Megumi Aimoto (Author), Yoshinobu Nagasawa (Author)
Format: Book
Published: Elsevier, 2018-05-01T00:00:00Z.
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