Protective Effects of Sesamin on Cytoxan-Induced Spermatogenesis Dysfunction by Regulating RNF8-ubH2A/ubH2B Pathways in Male Mice

• Main Authors: Dong-Mei Hai (Author), Jia-Wei Ren (Author), Yan-Nan Chi (Author), Rui-Juan Ye (Author), Ning Liu (Author), Lin Ma (Author), Xiao-Bing Lan (Author), Jing Wu (Author), Jian-Qiang Yu (Author), Jia-Mei Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most of the clinically infertile patients show spermatogenesis dysfunction. Cyclophosphamide, as an anticancer drug, can induce spermatogenesis dysfunction. Sesamin is the main bioactive component of natural lignans in sesame. It is abundant in sesame oil and has strong biological activities such as...