Expanding the Structural Diversity of DNA Methyltransferase Inhibitors

Expanding the Structural Diversity of DNA Methyltransferase Inhibitors

Inhibitors of DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug discovery. They are also chemical tools to understand the biochemistry of epigenetic processes. Herein, we report five distinct inhibitors of DNMT1 characterized in enzymatic inhibition assays that did not show...

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Main Authors: K. Eurídice Juárez-Mercado (Author), Fernando D. Prieto-Martínez (Author), Norberto Sánchez-Cruz (Author), Andrea Peña-Castillo (Author), Diego Prada-Gracia (Author), José L. Medina-Franco (Author)
Format: Book
Published: MDPI AG, 2020-12-01T00:00:00Z.
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