Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro

• Main Authors: Lijun Shan (Author), Linmei Gao (Author), Yuhao Chai (Author), Kun Li (Author), Jianmin Yu (Author), Fei Liang (Author), Jiangfeng Qin (Author), Ya Ni (Author), Peibei Sun (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sperm capacitation is a prerequisite for natural or in vitro fertilization. After capacitation, sperm become hyperactivated and undergo an acrosome reaction, which helps them penetrate the oocyte. Cordycepin, a bioactive compound first isolated from Cordyceps militaris, is an ade...