Nucleocapsid protein-based vaccine provides protection in mice against lethal Crimean-Congo hemorrhagic fever virus challenge.

• Main Authors: Marko Zivcec (Author), David Safronetz (Author), Dana P Scott (Author), Shelly Robertson (Author), Heinz Feldmann (Author)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2018-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Crimean-Congo hemorrhagic fever (CCHF) is an acute, often fatal viral disease characterized by rapid onset of febrile symptoms followed by hemorrhagic manifestations. The etiologic agent, CCHF orthonairovirus (CCHFV), can infect several mammals in nature but only seems to cause clinical disease in h...