Evaluation of the protective potential of antibody and T cell responses elicited by a novel preventative vaccine towards respiratory syncytial virus small hydrophobic protein

• Main Authors: Heather L. Torrey (Author), Valarmathy Kaliaperumal (Author), Yogesh Bramhecha (Author), Genevieve M. Weir (Author), Ann R. Falsey (Author), Edward E. Walsh (Author), Joanne M. Langley (Author), Bert Schepens (Author), Xavier Saelens (Author), Marianne M. Stanford (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The small hydrophobic (SH) glycoprotein of human respiratory syncytial virus (RSV) is a transmembrane protein that is poorly accessible by antibodies on the virion but has an ectodomain (SHe) that is accessible and expressed on infected cells. The SHe from RSV strain A has been formulated in DPX, a...