Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs

• Autores principales: Phuong Tran (Autor), Yong-Chul Pyo (Autor), Dong-Hyun Kim (Autor), Sang-Eun Lee (Autor), Jin-Ki Kim (Autor), Jeong-Sook Park (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2019-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic drugs (monoclonal antibodies) and small molecule drugs (nonbiologic anticancer drugs) based on effectiveness and safety p...