A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults.

• Main Authors: Vianney Tricou (Author), Nguyet Nguyen Minh (Author), Toi Pham Van (Author), Sue J Lee (Author), Jeremy Farrar (Author), Bridget Wills (Author), Hien Tinh Tran (Author), Cameron P Simmons (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is currently no licensed antiviral drug for treatment of dengue. Chloroquine (CQ) inhibits the replication of dengue virus (DENV) in vitro.A double-blind, randomized, placebo-controlled trial of CQ in 307 adults hospitalized for suspected DENV infection was conducted at the Hospital for Tropic...