Cardiac sodium channel inhibition by lamotrigine: In vitro characterization and clinical implications

Cardiac sodium channel inhibition by lamotrigine: In vitro characterization and clinical implications

Abstract Lamotrigine, approved for use as an antiseizure medication as well as the treatment of bipolar disorder, inhibits sodium channels in the brain to reduce repetitive neuronal firing and pathological release of glutamate. The shared homology of sodium channels and lack of selectivity associate...

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Main Authors: Lindsey Ingleby‐Talecki (Author), Sven C. vanDijkman (Author), Sean P. Oosterholt (Author), Oscar Della Pasqua (Author), Christina Winter (Author), Marianne Cunnington (Author), Linda Rebar (Author), Sergio Forero‐Schwanhaeuser (Author), Vickas Patel (Author), James A. Cooper (Author), Anthony Bahinski (Author), Khuram W. Chaudhary (Author)
Format: Book
Published: Wiley, 2022-08-01T00:00:00Z.
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3rd Floor Main Library

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