Application of chromosome microarray analysis and karyotyping in diagnostic assessment of abnormal Down syndrome screening results

• Main Authors: Han Kang (Author), Lingxi Wang (Author), Xingyu Li (Author), Chonglan Gao (Author), Yamei Xie (Author), Yu Hu (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Down syndrome (DS) is the most common congenital cause of intellectual disability and also leads to numerous metabolic and structural problems. This study aims to explore the application value of chromosomal microarray analysis (CMA) and karyotyping in prenatal diagnosis for preg...