Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi.

• Main Authors: Cristina Bosch-Navarrete (Author), Guiomar Pérez-Moreno (Author), Frederick Annang (Author), Rosario Diaz-Gonzalez (Author), Raquel García-Hernández (Author), Hedy Rocha (Author), Francisco Gamarro (Author), Carlos Cordón-Obras (Author), Miguel Navarro (Author), Ana Rodriguez (Author), Olga Genilloud (Author), Fernando Reyes (Author), Francisca Vicente (Author), Luis M Ruiz-Pérez (Author), Dolores González-Pacanowska (Author)
• Format: Bog
• Udgivet: Public Library of Science (PLoS), 2023-09-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Neglected diseases caused by kinetoplastid parasites are a health burden in tropical and subtropical countries. The need to create safe and effective medicines to improve treatment remains a priority. Microbial natural products are a source of chemical diversity that provides a valuable approach for...