The Synthesis and Preliminary Anticancer Evaluation of 6-Mercaptopurine -Methotrexate Conjugate as Possible Mutual Prodrug

Small molecules drug conjugate mutual prodrug design  (SMDC) composed of folate &lethal agent conjugate  , rigidly bonded via hydrophilic bridge& self immolative disulfide  bond   ;  represent new interesting approaches for cancer treatment , the component of SMDC intended to be as possible...

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Main Authors: Asmaa Safwan Al-darraji (Author), Mohamed H.Mohamed (Author)
Formato: Livro
Publicado em: College of Pharmacy University of Baghdad, 2019-06-01T00:00:00Z.
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