Interleukin-6 Contributes to Age-Related Alteration of Cytokine Production by Macrophages

Interleukin-6 Contributes to Age-Related Alteration of Cytokine Production by Macrophages

Here, we studied in vitro cytokine production by splenic macrophages obtained from young and aged BALB/c wild type (WT) and IL-6 knockout (IL-6 KO) mice. Relative to macrophages obtained from young WT mice given lipopolysaccharide (LPS), those from aged WT mice had decreased production of proinflamm...

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Main Authors: Christian R. Gomez (Author), John Karavitis (Author), Jessica L. Palmer (Author), Douglas E. Faunce (Author), Luis Ramirez (Author), Vanessa Nomellini (Author), Elizabeth J. Kovacs (Author)
Format: Book
Published: Hindawi Limited, 2010-01-01T00:00:00Z.
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