Intracellular Selection of Theophylline-Sensitive Hammerhead Aptazyme

• Váldodahkkit: Qinlin Pu (Dahkki), Shan Zhou (Dahkki), Xin Huang (Dahkki), Yi Yuan (Dahkki), Feng Du (Dahkki), Juan Dong (Dahkki), Gangyi Chen (Dahkki), Xin Cui (Dahkki), Zhuo Tang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2020-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Hammerhead ribozyme-based aptazyme (HHAz), inheriting the advantages of small size and high efficiency from the RNA-cleaving ribozyme and the specific recognition ability of aptamers to specific targets, exhibits the huge potential to be a transgene expression regulator. Herein, we report a selectio...