Different Apples, Same Tree: Visualizing Current Biological and Clinical Insights into CTLA-4 Insufficiency and LRBA and DEF6 Deficiencies

Cytotoxic T lymphocyte antigen-4 (CTLA-4) is a crucial immune checkpoint that is constitutively expressed in regulatory T (Treg) cells. Following T-cell activation, CTLA-4 is rapidly mobilized from its intracellular vesicle pool to the cell surface to control the availability of co-stimulatory B7 mo...

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Bibliographic Details
Main Authors: Laura Gámez-Díaz (Author), Markus G. Seidel (Author)
Format: Book
Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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