Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum induces non-selective cytotoxicity and P-glycoprotein inhibition

• Auteurs principaux: Trevor Burger (Auteur), Tsholofelo Mokoka (Auteur), Gerda Fouché (Auteur), Paul Steenkamp (Auteur), Vanessa Steenkamp (Auteur), Werner Cordier (Auteur)
• Format: Livre
• Publié: BMC, 2018-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background Solanum aculeastrum fruits are used by some cancer sufferers as a form of alternative treatment. Scientific literature is scarce concerning its anticancer activity, and thus the aim of the study was to assess the in vitro anticancer and P-glycoprotein inhibitory potential of extr...