The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells

• Main Authors: Andrew Parker (Author), Sally H. Cross (Author), Ian J. Jackson (Author), Rachel Hardisty-Hughes (Author), Susan Morse (Author), George Nicholson (Author), Emma Coghill (Author), Michael R. Bowl (Author), Steve D. M. Brown (Author)
• Format: Book
• Published: The Company of Biologists, 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitogen-activated protein kinase, MAP3K1, plays an important role in a number of cellular processes, including epithelial migration during eye organogenesis. In addition, studies in keratinocytes indicate that MAP3K1 signalling through JNK is important for actin stress fibre formation and cell migra...