Synthesis and Evaluation of the Antidepressant-like Properties of HBK-10, a Novel 2-Methoxyphenylpiperazine Derivative Targeting the 5-HT_1A and D₂ Receptors

• Главные авторы: Kinga Sałaciak (Автор), Natalia Malikowska-Racia (Автор), Klaudia Lustyk (Автор), Agata Siwek (Автор), Monika Głuch-Lutwin (Автор), Grzegorz Kazek (Автор), Justyna Popiół (Автор), Jacek Sapa (Автор), Henryk Marona (Автор), Dorota Żelaszczyk (Автор), Karolina Pytka (Автор)
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• Опубликовано: MDPI AG, 2021-07-01T00:00:00Z.
• Предметы: article
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The increasing number of patients reporting depressive symptoms requires the design of new antidepressants with higher efficacy and limited side effects. As our previous research showed, 2-methoxyphenylpiperazine derivatives are promising candidates to fulfill these criteria. In this study, we aimed...