Antisense oligonucleotides targeting exon 11 are able to partially rescue the NF2-related schwannomatosis phenotype in vitro

• Asıl Yazarlar: Núria Catasús (Yazar), Inma Rosas (Yazar), Sandra Bonache (Yazar), Alex Negro (Yazar), Miguel Torres-Martin (Yazar), Adrià Plana-Pla (Yazar), Hector Salvador (Yazar), Eduard Serra (Yazar), Ignacio Blanco (Yazar), Elisabeth Castellanos (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

NF2-related schwannomatosis (NF2-related SWN) is an autosomal dominant condition caused by loss of function variants in the NF2 gene, which codes for the protein Merlin and is characterized by the development of multiple tumors of the nervous system. The clinical presentation of the disease is varia...