Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status

• Автори: Yuko Miyagoe-Suzuki (Автор), Takashi Nishiyama (Автор), Miho Nakamura (Автор), Asako Narita (Автор), Fusako Takemura (Автор), Satoru Masuda (Автор), Narihiro Minami (Автор), Kumiko Murayama (Автор), Hirofumi Komaki (Автор), Yu-ichi Goto (Автор), Shin'ichi Takeda (Автор)
• Формат: Книга
• Опубліковано: Hindawi Limited, 2017-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Three to eight percent of female carriers of Duchenne muscular dystrophy (DMD) develop dystrophic symptoms ranging from mild muscle weakness to a rapidly progressive DMD-like muscular dystrophy due to skewed inactivation of X chromosomes during early development. Here, we generated human induced plu...