Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target

Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target

Show other versions (1)

In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich, chemical entities that comply with the following cri...

Full description

Saved in:
Bibliographic Details
Main Author: Denton, Helen (auth)
Other Authors: Major, Louise L. (auth), Smith, Terry K. (auth)
Format: Electronic Book Chapter
Language:English
Published: InTechOpen 2013
Subjects:
Pharmacology
pharmacology
toxicology
Assay
Enzyme
Molar concentration
Protein
Thermal shift assay
Trypanosoma brucei
Online Access:OAPEN Library: download the publication
OAPEN Library: description of the publication
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

OAPEN Library: download the publication
OAPEN Library: description of the publication

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items