Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target
In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich, chemical entities that comply with the following cri...
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Main Author: | Denton, Helen (auth) |
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Other Authors: | Major, Louise L. (auth), Smith, Terry K. (auth) |
Format: | Electronic Book Chapter |
Language: | English |
Published: |
InTechOpen
2013
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Online Access: | OAPEN Library: download the publication OAPEN Library: description of the publication |
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