Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies

Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While no...

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Bibliographische Detailangaben
1. Verfasser: Jordan, Bénédicte F. (auth)
Weitere Verfasser: Sonveaux, Pierre (auth)
Format: Elektronisch Buchkapitel
Sprache:Englisch
Veröffentlicht: InTechOpen 2011
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