Chapter Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry

A characteristic of many proteoforms, derived from a single gene, is their similarity regarding the composition of atoms, making their analysis very challenging. Many overexpressed recombinant proteins are strongly associated with this problem, especially recombinant therapeutic glycoproteins from l...

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Autor principal: Heikaus, Laura (auth)
Otros Autores: Schlüter, Hartmut (auth), Nurul Hidayah, Siti (auth), Gaikwad, Manasi (auth)
Formato: Electrónico Capítulo de libro
Lenguaje:inglés
Publicado: InTechOpen 2019
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