Molecular imaging in Parkinson's disease
The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychologica...
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| Glavni autor: | |
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| Format: | Elektronički Poglavlje knjige |
| Jezik: | engleski |
| Izdano: |
Firenze
Firenze University Press
2011
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| Serija: | Premio Tesi di Dottorato
18 |
| Teme: | |
| Online pristup: | OAPEN Library: download the publication OAPEN Library: description of the publication |
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| Sažetak: | The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus. |
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| Opis fizičkog objekta: | 1 electronic resource (68 p.) |
| ISBN: | 978-88-6655-041-9 9788866550419 9788866550372 9788892736450 |
| Pristup: | Open Access |