Study of intracellular signaling pathways in Chronic Myeloproliferative Neoplasms

A gain-of-function mutation in Janus kinase 2 (JAK2V617F) is at the basis of the majority of chronic myeloproliferative neoplasms (MPN). Enhanced activation of other downstream pathways including the PI3K/mTOR pathway has been documented as well. In this study we evaluated the effects of JAK1/2 inhi...

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Auteur principal: Martinelli, Serena (auth)
Format: Électronique Chapitre de livre
Langue:anglais
Publié: Florence Firenze University Press 2017
Collection:Premio Tesi di Dottorato 60
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