Study of intracellular signaling pathways in Chronic Myeloproliferative Neoplasms
A gain-of-function mutation in Janus kinase 2 (JAK2V617F) is at the basis of the majority of chronic myeloproliferative neoplasms (MPN). Enhanced activation of other downstream pathways including the PI3K/mTOR pathway has been documented as well. In this study we evaluated the effects of JAK1/2 inhi...
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Format: | Électronique Chapitre de livre |
Langue: | anglais |
Publié: |
Florence
Firenze University Press
2017
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Collection: | Premio Tesi di Dottorato
60 |
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Accès en ligne: | OAPEN Library: download the publication OAPEN Library: description of the publication |
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OAPEN Library: download the publicationOAPEN Library: description of the publication
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A1234.567 |
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