Gastrointestinally mediated food allergy causing Spondyloarthritis-like disease

• Asıl Yazarlar: Raithel M (Yazar), Finzel S (Yazar), Heussinger N (Yazar), Rieker RJ (Yazar), Baenkler HW (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Archives of Clinical Gastroenterology - Peertechz Publications, 2020-07-15.
• Konular: Case Report
• Online Erişim: Connect to this object online.

<p>Gastrointestinally-mediated food allergy (GMA) incidentally may cause non-erosive oligoarthritis.</p><p>A 56-year-old woman with seronegative spondyloarthritis observed arthritic flares following ingestion of certain foods. Blood analyses were unremarkable. Segmental gut lavage revealed plasmacellular infiltrates and eosinophilia in terminal ileum. Food allergen-specific IgE-analysis of lavage fluid showed significant polyvalent intestinal IgE-sensitization (>0.35kU/mg protein) towards wheat, rye, egg, soybean, pork, beef, nuts. Repeated exposure to the aforementioned foods caused arthritis within 48 hours; elimination diet engendered long-term remission. Seronegative local IgE-mediated GMA (type I) was diagnosed.</p><p>Especially seronegative rheumatoid arthritis and undifferentiated oligoarthritis should be scrutinized for food-related muscoloskeletal symptoms before initiating immunosuppression. </p>