Electrophysiological Profiling of Depression in the Elderly
<p>Frontostriatal system functioning has been proposed to underpin performance on executive functioning tasks; these structures are abnormally activated in adults with depression. In this study, the P200 and P300 event-related potentials (ERPs) were elicited during a classic two-tone auditor...
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| Main Authors: | , , , |
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| Format: | Book |
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Archives of Depression and Anxiety - Peertechz Publications,
2016-07-23.
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| Online Access: | Connect to this object online. |
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| Summary: | <p>Frontostriatal system functioning has been proposed to underpin performance on executive functioning tasks; these structures are abnormally activated in adults with depression. In this study, the P200 and P300 event-related potentials (ERPs) were elicited during a classic two-tone auditory oddball task to compare the electrophysiological profiles of elderly people (N = 54; Mean age = 85.46 ± 6.21) diagnosed with clinical depression ( n = 17), subthreshold depression ( n = 25) or no depression ( n = 12). The P200 results revealed higher amplitude and significantly longer latencies in depressed groups relative to non-depressed participants. Higher P300 amplitude, but shorter latencies, were observed in depressed relative to non-depressed participants. Findings are discussed in terms of cognitive information processing models of ERPs and the potential for non-cognitive factors to impact on the resulting electrophysiological profile. </p> |
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| DOI: | 10.17352/2455-5460.000012 |