Anti-VEGF Therapy Induces Proteinuria through Endothelial Disorganization Leading to Nephrin Decrease in Podocytes

• मुख्य लेखकों: Marianne Terrasse (लेखक), Florence Jouan (लेखक), Thibault Dolley-Hitze (लेखक), Yannick Arlot-Bonnemains (लेखक), Marc-Antoine (लेखक), Nathalie Rioux-Leclercq (लेखक), Nolwenn Lorcy (लेखक), Cécile Vigneau (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: International Journal of Immunotherapy and Cancer Research - Peertechz Publications, 2015-10-28.
• विषय: Research Article
• ऑनलाइन पहुंच: Connect to this object online.

<p><strong>Background:</strong> VEGF is involved in cancer development by stimulating neo-angiogenesis and tumor proliferation. Anti-angiogenic therapies, especially tyrosine kinase inhibitors such as sunitinib, have significantly improved cancer prognosis. Nevertheless, renal side...