A combination treatment of IFN-α2b and IFN-γ accelerates viral clearance and control inflammatory response in COVID-19: Preliminary results of a randomized controlled trial

• Main Authors: Esquivel-Moynelo Idelsis (Author), Pérez-Escribano Jésus (Author), Duncan-Roberts Yaquelin (Author), Vázquez-Blomquist Dania (Author), Bequet-Romero Mónica (Author), Báez-Rodríguez Lisandra (Author), Castro-Ríos Jésus (Author), Cobas-Cervantes Lisbeth (Author), Pagé-Calvet Ernesto (Author), Travieso-Pérez Saily (Author), Martinez-Suarez Claudia (Author), Campa-Legra Ivan (Author), Fernandez-Masso Julio (Author), Camacho-Rodriguez Hamlet (Author), Díaz-Gálvez Marisol (Author), Sin-Mayor Adriana (Author), García-Sánchez Maura (Author), Martínez-Martín Sara (Author), Alonso-Valdés Marel (Author), Hernández-Bernal Francisco (Author), Nodarse-Cuni Hugo (Author), Bello-Garcia Dianela (Author), Canaan-Haden Ayala Camila (Author), Gonzáles-Moya Isabel (Author), Beato-Canfuk Abrahan (Author), Vizcaino-Cesar Tania (Author), Guillén-Nieto Gerardo (Author), Muzio-González Verena (Author), Fish Eleanor (Author), Bello-Rivero Iraldo (Author)
• Format: Book
• Published: Annals of Antivirals and Antiretrovirals - Peertechz Publications, 2021-06-15.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>Background: There is in vitro evidence that a combination of IFN-α and IFN-γ acts synergistically to inhibit SARS-CoV replication. We conducted a randomized controlled clinical trial to evaluate the safety and therapeutic efficacy of administration of a combination of IFN-α and IFN-γ for CO...