Phenazopyridine abuse presenting with acute kidney injury, hemolytic anaemia and jaundice

<p>Phenazopyridine, an azo dye, is commonly used to relieve dysuria caused by bladder irritation or infection. We report the case of a 64-year-old lady who presented with unexplained sub-acute onset hemolytic anaemia followed by acute kidney injury (AKI) and jaundice. This created a diagnostic...

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Main Authors: Jaya Prakash Nath Ambinathan (Author), Mohamed Elbokyl (Author), Rory McQuillan (Author)
Format: Book
Published: Archives of Clinical Nephrology - Peertechz Publications, 2017-08-23.
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100 1 0 |a Jaya Prakash Nath Ambinathan  |e author 
700 1 0 |a  Mohamed Elbokyl  |e author 
700 1 0 |a Rory McQuillan  |e author 
245 0 0 |a Phenazopyridine abuse presenting with acute kidney injury, hemolytic anaemia and jaundice 
260 |b Archives of Clinical Nephrology - Peertechz Publications,   |c 2017-08-23. 
520 |a <p>Phenazopyridine, an azo dye, is commonly used to relieve dysuria caused by bladder irritation or infection. We report the case of a 64-year-old lady who presented with unexplained sub-acute onset hemolytic anaemia followed by acute kidney injury (AKI) and jaundice. This created a diagnostic dilemma until concealed phenazopyridine abuse was discovered. Discontinuation of Phenazopyridine improved renal function and hemoglobin level to baseline without any other intervention. Prompt urinalysis proved  crucial in solving the diagnostic challenge. We also present a review of literature highlighting the association of this commonly used medication with renal tubular dysfunction, interstitial nephritis and hemolytic anemia.</p> 
540 |a Copyright © Jaya Prakash Nath Ambinathan et al. 
546 |a en 
655 7 |a Case Report  |2 local 
856 4 1 |u https://doi.org/10.17352/acn.000023  |z Connect to this object online.