Cytotoxicity, genotoxicity, and mutagenicity of the active pharmaceutical ingredient nevirapine and a nevirapine-based drug on the plant species Allium cepa

• Main Authors: Juliana Souki Diniz (Author), Gabriel de Souza-Silva (Author), Clessius Ribeiro de Souza (Author), Leonardo Alvarenga de Paula Freitas (Author), Ana Luísa Souki Parreira (Author), Brennda Rocha Pena (Author), Marcos Paulo Gomes Mol (Author), Micheline Rosa Silveira (Author)
• Format: Book
• Published: Annals of Environmental Science and Toxicology - Peertechz Publications, 2023-05-23.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>The toxicity of the active pharmaceutical ingredient and nevirapine-based drug at analytical concentrations was evaluated under laboratory conditions, using Allium cepa seeds as a model. The germination index of the negative control was 86.8 ± 2.1. The concentrations of 6.42 and 9.54 mg/L o...