Chronic demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in peripheral T-cell lymphoma

<p>Malignant lymphoma can cause peripheral neuropathy through various mechanisms. We report the case of 67-year-old man with chronic motor and sensory axonal demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in serum and cerebrospinal fluid (CSF) as an initial prese...

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Main Authors: Salem Bahashwan (Author), Carolyne Croizier (Author), Xavier Moisset (Author), Romain Guièze (Author), Bertrand Evrard (Author), Olivier Tournilhac (Author), Jacques-Olivier Bay (Author), Richard Lemal (Author)
Formato: Livro
Publicado em: Archives of Hematology Case Reports and Reviews - Peertechz Publications, 2019-05-23.
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MARC

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042 |a dc 
100 1 0 |a Salem Bahashwan  |e author 
700 1 0 |a  Carolyne Croizier  |e author 
700 1 0 |a  Xavier Moisset  |e author 
700 1 0 |a  Romain Guièze  |e author 
700 1 0 |a  Bertrand Evrard  |e author 
700 1 0 |a  Olivier Tournilhac  |e author 
700 1 0 |a  Jacques-Olivier Bay  |e author 
700 1 0 |a Richard Lemal  |e author 
245 0 0 |a Chronic demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in peripheral T-cell lymphoma 
260 |b Archives of Hematology Case Reports and Reviews - Peertechz Publications,   |c 2019-05-23. 
520 |a <p>Malignant lymphoma can cause peripheral neuropathy through various mechanisms. We report the case of 67-year-old man with chronic motor and sensory axonal demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in serum and cerebrospinal fluid (CSF) as an initial presentation of peripheral T-cell lymphoma, not otherwise specified. The patient was treated with chemotherapy for T-cell lymphoma, and achieved complete remission.  Motor function recovered completely and sensory function improved. Neurological improvement was concurrent with the disappearance of serum and CSF anti-ganglioside GQ1b antibodies. This is the first report of chronic demyelinating polyneuropathy associated with anti-ganglioside GQ1b antibodies in peripheral T-cell lymphoma.</p> 
540 |a Copyright © Salem Bahashwan et al. 
546 |a en 
655 7 |a Case Report  |2 local 
856 4 1 |u https://doi.org/10.17352/ahcrr.000017  |z Connect to this object online.