Identification of Combinatorial Drugs that Synergistically Kill both Eribulin-Sensitive and Eribulin-Insensitive Tumor Cells

• Main Authors: Richard J Rickles (Author), Junji Matsui (Author), Ping Zhu (Author), Yasuhiro Funahashi (Author), Jill M Grenier (Author), Janine Steiger (Author), Nanding Zhao (Author), Bruce A Littlefield (Author), Kenichi Nomoto (Author), Toshimitsu Uenaka (Author)
• Format: Book
• Published: Global Journal of Cancer Therapy - Peertechz Publications, 2015-11-04.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>Eribulin sensitivity was examined in a panel of twenty-five human cancer cell lines representing a variety of tumor types, with a preponderance of breast and lung cancer cell lines. As expected, the cell lines vary in sensitivity to eribulin at clinically relevant concentrations. To identif...