Cytochrome P450 Enzymes, Drug Transporters and their Role in Pharmacokinetic Drug-Drug Interactions of Xenobiotics: A Comprehensive Review
<p>Drug-Drug interactions (DDI) is a serious clinical issue. An important mechanism underlying of DDI, is induction or inhibition of drug metabolizing enzymes (DMEs) and transporters that mediate metabolism, cellular uptake and effl ux of xenobiotics. DDI cannot be avoided in many cases, as th...
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Open Journal of Chemistry - Peertechz Publications,
2017-07-11.
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