Synthesis, characterization and cytotoxic activity of betulinic acid glucosides against human myeloid leukemia and human T-4 lymphoblastoid cell lines / Mohd Tajudin Mohd Ali and Nurhana Faujan

• मुख्य लेखकों: Mohd Ali, Mohd Tajudin (लेखक), Faujan, Nurhana (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: 2016-06.
• विषय: Article; PeerReviewed
• ऑनलाइन पहुंच: Link Metadata

Glycosylation of betulinic acid with B-D-glucose-pentaacetate was successfully synthesized in the presence of boron trifluoro etherate (BF3.Et2O) in pyridine to give betulinic acid bisglucoside in 92.8% yield. Further treatment of bisglucosides with methanol and sodium metal produced high polarity b...