Arama Sonuçları - Charlotte M. Deane

Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains Yazar: Lewis Chinery, Jeliazko R. Jeliazkov, Charlotte M. Deane

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Current strategies for detecting functional convergence across B-cell receptor repertoires Yazar: Matthew I. J. Raybould, Anthony R. Rees, Charlotte M. Deane

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Looking for therapeutic antibodies in next-generation sequencing repositories Yazar: Konrad Krawczyk, Matthew I. J. Raybould, Aleksandr Kovaltsuk, Charlotte M. Deane

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A computational method for immune repertoire mining that identifies novel binders from different clonotypes, demonstrated by identifying anti-pertussis toxoid antibodies Yazar: Eve Richardson, Jacob D. Galson, Paul Kellam, Dominic F. Kelly, Sarah E. Smith, Anne Palser, Simon Watson, Charlotte M. Deane

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Challenges in antibody structure prediction Yazar: Monica L. Fernández-Quintero, Janik Kokot, Franz Waibl, Anna-Lena M. Fischer, Patrick K. Quoika, Charlotte M. Deane, Klaus R. Liedl

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Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope Yazar: Wing Ki Wong, Sarah A. Robinson, Alexander Bujotzek, Guy Georges, Alan P. Lewis, Jiye Shi, James Snowden, Bruck Taddese, Charlotte M. Deane

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Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics Yazar: Rahul Khetan, Robin Curtis, Charlotte M. Deane, Johannes Thorling Hadsund, Uddipan Kar, Konrad Krawczyk, Daisuke Kuroda, Sarah A. Robinson, Pietro Sormanni, Kouhei Tsumoto, Jim Warwicker, Andrew C.R. Martin

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A comparative study of the developability of full-length antibodies, fragments, and bispecific formats reveals higher stability risks for engineered constructs Yazar: Itzel Condado-Morales, Fabian Dingfelder, Isabel Waibel, Oliver M. Turnbull, Bhargav Patel, Zheng Cao, Jais Rose Bjelke, Susanne Nedergaard Grell, Anja Bennet, Alissa M. Hummer, Matthew I. J. Raybould, Charlotte M. Deane, Thomas Egebjerg, Nikolai Lorenzen, Paolo Arosio

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