Search Results - Isaac Chen

Isaac Chen

Han-chiao Isaac Chen is a neurosurgeon at the Presbyterian Medical Center of Philadelphia and the Veteran's Administration Medical Center. The Chen Laboratory works to "develop novel methods for restoring the function of the brain after it has been damaged by combining aspects of stem cell biology, neural tissue engineering, and neural interface technologies."

In November 2017 it was reported that a team including Chen has successfully implanted brain organoids into rodents.

Dr. Chen has made notable contributions to the field of human brain organoids. His work in the Cell journal Stem Cell discusses the controversial topic of the ethics of brain chimeras. Provided by Wikipedia
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    Traumatic Brain Injury as a Systems Neuroscience Problem by Isaac Chen

    Published 2017
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    Comparative AAV-eGFP Transgene Expression Using Vector Serotypes 1-9, 7m8, and 8b in Human Pluripotent Stem Cells, RPEs, and Human and Rat Cortical Neurons by Thu T. Duong, James Lim, Vidyullatha Vasireddy, Tyler Papp, Hung Nguyen, Lanfranco Leo, Jieyan Pan, Shangzhen Zhou, H. Isaac Chen, Jean Bennett, Jason A. Mills

    Published 2019
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    Single cell phototransfection of mRNAs encoding SARS-CoV2 spike and nucleocapsid into human astrocytes results in RNA dependent translation interference by Hyun-Bum Kim, Quentin Brosseau, Julia Radzio, Jinhui Wang, Hiromi Muramatsu, Da Kuang, M. Sean Grady, H. Isaac Chen, John A. Wolf, Alexandra V. Ulyanova, Tamas Bartfai, Junhyong Kim, Norbert Pardi, Jai-Yoon Sul, Paulo Arratia, James Eberwine

    Published 2024
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