A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation by Matthew J. Winter, Yosuke Ono, Jonathan S. Ball, Anna Walentinsson, Erik Michaelsson, Anna Tochwin, Steffen Scholpp, Charles R. Tyler, Steve Rees, Malcolm J Hetheridge, Mohammad Bohlooly-Y

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Selecting the right therapeutic target for kidney disease by Lisa Buvall, Robert I. Menzies, Julie Williams, Kevin J. Woollard, Chanchal Kumar, Anna B. Granqvist, Maria Fritsch, Denis Feliers, Anna Reznichenko, Davide Gianni, Slavé Petrovski, Claus Bendtsen, Mohammad Bohlooly-Y, Carolina Haefliger, Regina Fritsche Danielson, Pernille B. L. Hansen

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Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression by Vian Azzu, Michele Vacca, Ioannis Kamzolas, Zoe Hall, Jack Leslie, Stefania Carobbio, Samuel Virtue, Susan E. Davies, Agnes Lukasik, Martin Dale, Mohammad Bohlooly-Y, Animesh Acharjee, Daniel Lindén, Guillaume Bidault, Evangelia Petsalaki, Julian L. Griffin, Fiona Oakley, Michael E.D. Allison, Antonio Vidal-Puig

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Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice by Daniel Lindén, Andrea Ahnmark, Piero Pingitore, Ester Ciociola, Ingela Ahlstedt, Anne-Christine Andréasson, Kavitha Sasidharan, Katja Madeyski-Bengtson, Magdalena Zurek, Rosellina M. Mancina, Anna Lindblom, Mikael Bjursell, Gerhard Böttcher, Marcus Ståhlman, Mohammad Bohlooly-Y, William G. Haynes, Björn Carlsson, Mark Graham, Richard Lee, Sue Murray, Luca Valenti, Sanjay Bhanot, Peter Åkerblad, Stefano Romeo

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