Preface by Enrico Garaci, Patrizia Popoli

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The role of the Istituto Superiore di Sanità as the competent authority for Phase I trials in the translation of advanced therapies by Patrizia Popoli, Maria Francesca Cometa, Fulvia Fabi, Annarita Meneguz

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P2X7 Receptor Agonist 2'(3')-O-(4-Benzoylbenzoyl)ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington's Disease by Alberto Martire, Rita Pepponi, Francesco Liguori, Cinzia Volonté, Cinzia Volonté, Patrizia Popoli

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Insight into the Role of the STriatal-Enriched Protein Tyrosine Phosphatase (STEP) in A2A Receptor-Mediated Effects in the Central Nervous System by Maria Rosaria Domenici, Cinzia Mallozzi, Rita Pepponi, Ida Casella, Valentina Chiodi, Antonella Ferrante, Patrizia Popoli

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Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis by Savina Apolloni, Susanna Amadio, Chiara Parisi, Alessandra Matteucci, Rosa L. Potenza, Monica Armida, Patrizia Popoli, Nadia D'Ambrosi, Cinzia Volonté

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Towards a European harmonization of health technology assessment recommendations executive paper of European regulatory conference focused on the EU commission proposal to harmoniz... by Lucia Gozzo, Kenneth Paterson, Olivier Wong, Francis Megerlin, Jan Geldmacher, Patrizia Popoli, Claudio Jommi, Frank-Ulrich Fricke, Oriol De Solà-Morales, Isao Kamae, Guido Rasi, Filippo Drago, Filippo Drago, Filippo Drago

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