Resultados da pesquisa - Robert C. Penland

Potassium homeostasis and therapeutic intervention with sodium zirconium cyclosilicate: A model‐informed drug development case study Por Lindsay E. Clegg, Lulu Chu, Mats Nagard, David W. Boulton, Robert C. Penland

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Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model Por Victor Sokolov, Victor Sokolov, Tatiana Yakovleva, Robert C. Penland, David W. Boulton, Weifeng Tang

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A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes Por Victor Sokolov, Tatiana Yakovleva, Leonid Stolbov, Robert C. Penland, David Boulton, Joanna Parkinson, Weifeng Tang

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Cardiac safety implications of hNav1.5 blockade and a framework for preclinical evaluation Por Gul eErdemli, Albert M Kim, Haisong eJu, Clayton eSpringer, Robert C Penland, Peter K Hoffmann

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Differentiating the Sodium‐Glucose Cotransporter 1 Inhibition Capacity of Canagliflozin vs. Dapagliflozin and Empagliflozin Using Quantitative Systems Pharmacology Modeling Por Victor Sokolov, Tatiana Yakovleva, Lulu Chu, Weifeng Tang, Peter J. Greasley, Susanne Johansson, Kirill Peskov, Gabriel Helmlinger, David W. Boulton, Robert C. Penland

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Quantitative Systems Pharmacology: An Exemplar Model‐Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development Por Gabriel Helmlinger, Victor Sokolov, Kirill Peskov, Karen M. Hallow, Yuri Kosinsky, Veronika Voronova, Lulu Chu, Tatiana Yakovleva, Ivan Azarov, Daniel Kaschek, Artem Dolgun, Henning Schmidt, David W. Boulton, Robert C. Penland

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