Amyloid-beta clearance in Alzheimer's disease

• Yazar: Robert Marr (auth)
• Diğer Yazarlar: Eliezer Masliah (auth)
• Materyal Türü: Elektronik Kitap Bölümü
• Dil: İngilizce
• Baskı/Yayın Bilgisi: Frontiers Media SA 2015
• Seri Bilgileri: Frontiers Research Topics
• Konular: Neurosciences; amyloid-beta; Signal Transduction; Proteases; LDL receptors; Clearance; Alzheimer's disease
• Online Erişim: DOAB: download the publication; DOAB: description of the publication

Strong evidence continues to accumulate indicating that amyloid-beta (Aß) is a central part of Alzheimer's disease (AD) pathogenesis in spite of the negative evidence coming from failed clinical trials. Therefore, mechanisms of clearance of Aß are of great interest in understanding AD pathogene...