Antibody Fc Engineering: Towards Better Therapeutics

• Yazar: Rui Gong (auth)
• Diğer Yazarlar: Tianlei Ying (auth)
• Materyal Türü: Elektronik Kitap Bölümü
• Dil: İngilizce
• Baskı/Yayın Bilgisi: Frontiers Media SA 2018
• Seri Bilgileri: Frontiers Research Topics
• Konular: Medicine; effector function; Fc receptor; heterodimeric Fc; Fc-fusion protein; monomeric Fc; Monoclonal antibody; Fc engineering
• Online Erişim: DOAB: download the publication; DOAB: description of the publication

Monoclonal antibodies and Fc-fusion proteins used clinically are Fc-based therapeutics that grow fastest in the pharmaceutical industry. Since they both contain an Fc fragment, engineering of Fc fragments could be a platform for improving Fc-based drug efficacy. Fc engineering includes various aspec...